The Fugitive (1963)

Kimble arrives in the factory town of Hempstead Mills, West Virginia to assist Andrew McCallister, his longtime mentor whom is dying from lung cancer which he is confined to a wheelchair. McCallister's vigorous anti-smog campaign has earned him a reputation as a local crackpot. But the old man plans to go out with a bang; by having a bomb hidden in a package where he has Kimble deliver to the local factory. But when McCallister discovers that a group of school children will be inside the factory during a school tour at the time of the explosion, he dispatches Kimble to evacuate the building and deactivate the bomb before time runs out.